Department of Biological Science

Professor Emeritus
M.D., University of Pavia (Italy) Medical School, 1947

Curriculum vitae

Obituary

Major Research Accomplishments

Graziadei was the first to suggest, and then to demonstrate, that olfactory receptor neurons were continually generated in vivo and that the population of globose basal cells serves as progenitors for the newly born neurons. He showed that olfactory neuron axons were critical in inducing the formation of their normal target, the olfactory bulb, during normal development. Using embryonic transplants, he showed that these axons could even invade and form synapse-like structures with CNS neurons in a wide range of other brain structures.

Selected Publications

Dryer, L., and P. P. C. Graziadei. 1996. Synaptology of the olfactory bulb of an elasmobranch fish, Sphyrna tiburo. Anatomy and Embryology 193:101-114.

Magrassi, L., and P. P. C. Graziadei. 1996. Lineage specification of olfactory neural precursor cells depends on continuous cell interactions. Developmental Brain Research 96:11-27.

Morrison, E. E., and P. P. C. Graziadei. 1996. An ultrastructural study of glomeruli associated with vomeronasal organs transplanted into the rat CNS. Anatomy and Embryology 193:331-339.

Ichikawa, M., T. Osada, and P. P. C. Graziadei. 1995. Coculture of the vomeronasal organ and olfactory bulb of the fetal rat. Anatomy and Embryology 192:417-426.

Koo, H., and P. P. C. Graziadei. 1995. Eye primordium transplantation in Xenopus embryo. Anatomy and Embryology 191:155-170.

Koo, H., and P. P. C. Graziadei. 1995. Cell-migration from the transplanted olfactory placode in Xenopus. Anatomy and Embryology 191:171-181.

Magrassi, L., and P. P. C. Graziadei. 1995. Cell-death in the olfactory epithelium. Anatomy and Embryology 192:77-87.

Morrison, E. E., and P. P. C. Graziadei. 1995. Transplantation of postnatal vomeronasal organ in the CNS of newborn rats. Anatomy and Embryology 191:319-327.