Florida State University, (contact info)
Ph.D. Botany, 1992, North Carolina State Univ.
Cell and Molecular Biology, within the Department of Biological Science, FSU.
Molecular Biophysics, inter-departmental, FSU
We are investigating the structure and function of chromosomes during meiosis, when chromosomes are recombined, shuffled, and reduced to the haploid state (during production of sperm or eggs). High-resolution deconvolution microscopy is used to collect multi-wavelength three-dimensional optical reconstructions of whole nuclei in meiotic cells of higher plants. Specific DNA sequences are localized within the nucleus by fluorescence in situ hybridization (FISH), and sophisticated software is used to analyze the resulting spatial and quantitative image data. Having adapted novel techniques for 3D FISH with plant meiotic chromosomes, we are now working on two related projects, the analysis of meiotic telomere behavior and the development of a new cytogenetic map of the maize genome (cytomaize.org).
- Annotated DAPI images of meiotic prophase substages,
(leptotene, zygotene, pachytene, diplotene, diakinesis);
- Telomere FISH analysis of the bouquet stage;
Whole chromosome painting analysis of chromosome pairing;
- TGMV geminvirus intranuclear localization.
- 3D Images of desynaptic (dy, dsy1) mutants.
PUBLICATIONS ; online links and image data links
STARTUP page, webstart1.html, quick links for Bass lab
SEMINAR SERIES, Biology Colloquium, and others
FACULTY SEARCHES in biology
stay tuned -<-you are here EEE